c) The root of Aspalathus
indicus (Fabaceae) was cited as a cure for tooth ache (Jagga Rao et
al., 1933). Aspalathus is a large African genus with no
representatives in India. Therefore, this is a case of botanical
misidentification, yet there must have been some reason for using the
generic name Aspalathus. The samskirt and telugu
names for the plant are the same, shiva nimba. The word nimba
has misdirected the search to the citrus family, but the descriptions of
the plant do not tally. Species of Aspalathus are described as
‘heath-like’ plants. How does a heath plant look like was not solved
till a visit to England. A few visits to the east coastal sandy areas
finally helped to determine the identity of the plant as Indigofera
aspalathoides, a heath-like plant, whose root has a local
anaesthetic effect.
d) The samskrit
names tavakshira and tvaksira are orthographic variants of
the same name applied to two different species. One is Bambusa
arundinacea (a bamboo) and the other is the unrelated Curcuma
angustifolia, a relative of the turmeric plant. The rhizomes of the
two species which are used in medicine look alike when dry. Arguments
persist in this case, though the bamboo rhizomes do not contain any
essential oils, while those of the other species do, which should be of
help.
e) The samskrit
name svarna kshira (golden milk) refers to the golden yellow
milky latex, basing on which two unrelated species are cited for use: Euphorbia
thomsoniana (Euphorbiaceae) and Argemone mexicana (Papaveraceae).
Euphorbia thomsoniana is native to India while Argemone
mexicana is an introduction from south America, less than two
hundred years ago, and so could not have been incorporated into the samhithas.
This is an easier issue, yet many do not agree, probably because the
exotic species is abundant, easily available and cheaper.
There
are several such problems in Indian medicinal plants. The question of
the identity of medicinal plants is a serious one requiring very
concerted efforts. A little bit of skepticism on the decisions, till
repeated efforts lead to the same conclusion, is a sensible option.
STANDARDISATION
AND QUALIFTY CONTROL OF MEDICINAL PLANTS AND
HERBAL MEDICINES
Standardisation of indigenous herbal drugs is a vexing problem in most
countries. There are very stringent procedures for pharmaceutical
standardisation in biomedicine. The international pharmacopoeia
(Anonymous, 1991) sets standards for several chemical constituents. It
is near impossible to apply a similar rigour to indigenous herbal drugs,
for various reasons.
The WHO has issued the
following guidelines for the assessment of herbal medicine (WHO, 1991):
a) Quality assessment:
crude plant material, plant preparation and finished product;
b) Stability: shelf
life;
c) Safety assessment:
documentation of safety based on experience or toxicology studies; and
d) Assessment of
efficacy: documented evidence of traditional use and/or activity
determination on animal or human models.
Unless
a suitable legislation is put in place, no amount of recommendation,
from whosoever, will be enforceable.
The steps in
standardisation and quality control are:
a) determining the
identity of the plants from classical texts and equating it to
scientific botanical identity;
b) ensuring that the
correctly identified raw material is supplied and used;
c) ensuring that the
correct formulation and the correct quantities, are used; and
d) ensuring that the
correct procedures of preparation, storage and packaging are adopted.
Problems exist at each
one of the above phases. The remedies are;
a)
adequately trained Ayurvedists and plant taxonomists should be involved
in establishing the identity of
plants;
b) the identity of the
crude drugs supplied should be checked by reference to pharmacognostic
data (for example, Narayana Aiyer and Lokammal, 1963);
c) herbal formulations
should be based on authentic and recognised documents available for
different indigenous systems (Ayurveda-Anonymous,
1978; Siddha-Anonymous 1989; Unani-Daljithsimha,
1974; Eastern medicine-Said, 1969). Any formulation outsides the recognised
documents should be approved by a recognised body;
d) modern facilities of
storage, preservation, product preparation, packaging, should be adopted,
to check product deterioration
.